Mass Spectrometry Quiz

1.
Mass spectrometers known as calutrons were used for the industrial separation of uranium isotopes during the Manhattan Project. A large amount of copper was needed to make their magnetic coils. How was the highly-valued metal obtained during the war?
- By confiscating almost year-round copper production from mines in the Belgian Congo
- By purchasing discarded copper stills from the Federal distillery in Port Melbourne
- By replacing copper with silver borrowed from the West Point Bullion Depository
Your answer:

Correct answer:

During the war, copper was preferably used for the production of brass shell casings and it was not available for the construction of calutrons. The designers came up with the idea of replacing copper with silver. They borrowed about 13,300 tons of silver from the West Point Bullion Depository in West Point, NY. After the war, the silver was returned to the Treasury with virtually no loss.
2.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?
- Electron ionization
- Fast atom bombardment
- Matrix-assisted laser desorption/ionization
Your answer:

Correct answer:

Mass spectrometry was used to sequence peptides for the first time in 1959 when K. Biemann described an innovative method based on the reduction of small peptides to polyamino alcohols with characteristic EI spectra. [https://doi.org/10.1021/ja01518a069]
3.
What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?
- The particle follows a curved path and continues to follow this path until it forms a complete circle
- Neither the trajectory nor the velocity of the particle changes
- The particle either accelerates or decelerates, depending on the field direction and the particle charge sign
Your answer:

Correct answer:

If a positive charge is moving in the same direction as the electric field vector the particle's velocity will increase. If it is moving in the opposite direction it will decelerate. If a negative charge is moving in the same direction as the electric field vector the particle will decelerate. If it is moving in the opposite direction it will accelerate.
4.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?
- Burnaby Munson and Frank H. Field
- Michael Barber
- Hans-Dieter Beckey
Your answer:

Correct answer:

Chemical ionization was discovered in the laboratories of the Humble Oil and Refining Company in Baytown, TX. Munson and Field’s seminal paper on chemical ionization was published in 1966. [https://doi.org/10.1021/ja00964a001]
5.
Lunar craters are usually named after scientists and explorers. One of the craters on the Moon is named after a prominent scientist in the field of mass spectrometry. Who is named after?
- Francis William Aston
- Wolfgang Paul
- John Bennett Fenn
Your answer:

Correct answer:

Aston is a 44-kilometer lunar impact crater located along the northwestern limb of the Moon. The crater was named in honor of Francis W. Aston.
6.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?
- Slovakia
- Czechia
- Poland
Your answer:

Correct answer:

The parents of John Zelený, Antonín Zelený and Josefa Pitková, came from Křídla, a small village near Žďár nad Sázavou in Austria-Hungary (now the Czech Republic).
7.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?
- Double-focusing mass spectrometer
- Time-of-flight mass spectrometer
- Quadrupole mass spectrometer
Your answer:

Correct answer:

Viking 1 carried two mass spectrometers, both equipped with double-focusing analyzers and electron ionization sources. The first spectrometer with a Mattauch-Herzog geometry was designed by Alfred Nier; it was intended to analyze the upper atmosphere of Mars. The second one with a Nier- Johnson geometry was part of the GC/MS apparatus designed by Klaus Biemann. It was used to analyze the regolith and the atmosphere at the landing site.
8.
Who made molecular elephants fly?
- John B. Fenn
- Joseph J. Thomson
- W. and O. Wright
Your answer:

Correct answer:

John Fenn was awarded Nobel Prize in Chemistry in 2002 for his work related to electrospray ionization of biological macromolecules. His famous phrase, "we made elephants fly" refers to the ability of electrospray to generate gas-phase ions from big protein molecules.
9.
List these compounds according to their increasing mass: hydrazine (H4N2), oxygen (O2), methanol (CH4O).
- Hydrazine, oxygen, methanol
- Methanol, hydrazine, oxygen
- Oxygen, methanol, hydrazine
Your answer:

Correct answer:

The monoisotopic masses of these compounds are 31.989829 Da (oxygen), 32.026215 Da (methanol), and 32.037448 Da (hydrazine).
10.
What is the electric charge of an ion with m/z = m?
- 1 C
- 1.602 176 634 x 10^-19 C
- 1 eV
Your answer:

Correct answer:

The particle carries one elementary charge, the value of which is 1.602 176 634 × 10⁻¹⁹ C (exactly).

Mass Spectrometry Quiz

Mass Spectrometry Quiz

Thank you for taking our quiz!

1.
Mass spectrometers known as calutrons were used for the industrial separation of uranium isotopes during the Manhattan Project. A large amount of copper was needed to make their magnetic coils. How was the highly-valued metal obtained during the war?

2.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?

3.
What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?

4.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

5.
Lunar craters are usually named after scientists and explorers. One of the craters on the Moon is named after a prominent scientist in the field of mass spectrometry. Who is named after?

6.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

7.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

8.
Who made molecular elephants fly?

9.
List these compounds according to their increasing mass: hydrazine (H4N2), oxygen (O2), methanol (CH4O).

10.
What is the electric charge of an ion with m/z = m?

Czech Museum
of Mass Spectrometry

Our partners

Mass Spectrometry Quiz

Mass Spectrometry Quiz

Thank you for taking our quiz!

1. Mass spectrometers known as calutrons were used for the industrial separation of uranium isotopes during the Manhattan Project. A large amount of copper was needed to make their magnetic coils. How was the highly-valued metal obtained during the war?

2. What ionization technique was used for the first sequencing of peptides by mass spectrometry?

3. What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?

4. Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

5. Lunar craters are usually named after scientists and explorers. One of the craters on the Moon is named after a prominent scientist in the field of mass spectrometry. Who is named after?

6. John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

7. Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

8. Who made molecular elephants fly?

9. List these compounds according to their increasing mass: hydrazine (H4N2), oxygen (O2), methanol (CH4O).

10. What is the electric charge of an ion with m/z = m?

Czech Museumof Mass Spectrometry

Our partners

1.
Mass spectrometers known as calutrons were used for the industrial separation of uranium isotopes during the Manhattan Project. A large amount of copper was needed to make their magnetic coils. How was the highly-valued metal obtained during the war?

2.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?

3.
What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?

4.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

5.
Lunar craters are usually named after scientists and explorers. One of the craters on the Moon is named after a prominent scientist in the field of mass spectrometry. Who is named after?

6.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

7.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

8.
Who made molecular elephants fly?

9.
List these compounds according to their increasing mass: hydrazine (H4N2), oxygen (O2), methanol (CH4O).

10.
What is the electric charge of an ion with m/z = m?

Czech Museum
of Mass Spectrometry