Mass Spectrometry Quiz

1.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?
- Electron ionization
- Fast atom bombardment
- Matrix-assisted laser desorption/ionization
Your answer:

Correct answer:

Mass spectrometry was used to sequence peptides for the first time in 1959 when K. Biemann described an innovative method based on the reduction of small peptides to polyamino alcohols with characteristic EI spectra. [https://doi.org/10.1021/ja01518a069]
2.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?
- Burnaby Munson and Frank H. Field
- Michael Barber
- Hans-Dieter Beckey
Your answer:

Correct answer:

Chemical ionization was discovered in the laboratories of the Humble Oil and Refining Company in Baytown, TX. Munson and Field’s seminal paper on chemical ionization was published in 1966. [https://doi.org/10.1021/ja00964a001]
3.
What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?
- The particle follows a curved path and continues to follow this path until it forms a complete circle
- Neither the trajectory nor the velocity of the particle changes
- The particle either accelerates or decelerates, depending on the field direction and the particle charge sign
Your answer:

Correct answer:

If a positive charge is moving in the same direction as the electric field vector the particle's velocity will increase. If it is moving in the opposite direction it will decelerate. If a negative charge is moving in the same direction as the electric field vector the particle will decelerate. If it is moving in the opposite direction it will accelerate.
4.
How many elements of the periodic table have only a single stable isotope?
- 0
- 15
- 26
Your answer:

Correct answer:

These so-called monoisotopic elements are beryllium, fluorine, sodium, aluminum, phosphorus, scandium, vanadium, manganese, cobalt, arsenic, rubidium, yttrium, niobium, rhodium, indium, iodine, cesium, lanthanum, praseodymium, europium, terbium, holmium, thulium, lutecium, rhenium, and gold.
5.
What is the electric charge of an ion with m/z = m?
- 1 C
- 1.602 176 634 x 10^-19 C
- 1 eV
Your answer:

Correct answer:

The particle carries one elementary charge, the value of which is 1.602 176 634 × 10⁻¹⁹ C (exactly).
6.
Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?
- Berlin, Germany
- Ostrava, Czechia
- Klosterneuburg, Austria
Your answer:

Correct answer:

Josef Mattauch was born in 1895 in the city of Mährisch Ostrau, in what is now the Czech Republic, then part of the Austrian-Hungarian Empire.
7.
Who built the first mass spectrometer in Czechia?
- Čermák, Hanuš, Jech, Cabicar
- Červinka, Dědek, Ferles
- Jára Cimrman
Your answer:

Correct answer:

The first mass spectrometer in the country was built in the Laboratory of Physical Chemistry of the Czechoslovak Academy of Sciences. Four young scientists, Vladimír Čermák, Vladimír Hanuš, Čestmír Jech and Josef Cabicar, took part in its construction. At the time of the post-war shortage, it was very difficult to find the necessary components; some parts originated from captured German military equipment. The mass spectrometer was of the Nier type with simple focusing and 60° magnetic field, pumped by a mercury diffusion pump. The device was completed after two years, in 1953. The construction of this instrument was an extraordinary achievement awarded a year later by the State Prize. [Z. Herman, Chem. Listy 104, 955, 2010]
8.
Who first reported the fragmentation after the gamma hydrogen rearrangement to an unsaturated group via a sixmembered intermediate?
- A. J. C. Nicholson
- F. W. McLafferty
- F. Tureček
Your answer:

Correct answer:

It was first reported by Australian A. J. C. Nicholson in 1954 (Trans. Faraday Soc. 50: 1067-1073). The reaction description was published five years later (Anal. Chem. 1959, 31: 82–87) by the American chemist Fred McLafferty, by whose name we now refer to the rearrangement (McLafferty rearrangement).
9.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?
- Double-focusing mass spectrometer
- Time-of-flight mass spectrometer
- Quadrupole mass spectrometer
Your answer:

Correct answer:

Viking 1 carried two mass spectrometers, both equipped with double-focusing analyzers and electron ionization sources. The first spectrometer with a Mattauch-Herzog geometry was designed by Alfred Nier; it was intended to analyze the upper atmosphere of Mars. The second one with a Nier- Johnson geometry was part of the GC/MS apparatus designed by Klaus Biemann. It was used to analyze the regolith and the atmosphere at the landing site.
10.
Joseph John Thomson (1856 - 1940), Nobel laureate in physics, is credited with the invention of the mass spectrometer, the discovery of the electron and isotopes of stable elements. A lesser-known fact is his father's profession. What was it?
- Electrical engineer
- Owner of an antiquarian bookshop
- Circus ringmaster
Your answer:

Correct answer:

His father, Joseph James Thomson, ran an antiquarian bookshop founded by Thomson’s great-grandfather. [Wikipedia]

Mass Spectrometry Quiz

Mass Spectrometry Quiz

Thank you for taking our quiz!

1.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?

2.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

3.
What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?

4.
How many elements of the periodic table have only a single stable isotope?

5.
What is the electric charge of an ion with m/z = m?

6.
Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?

7.
Who built the first mass spectrometer in Czechia?

8.
Who first reported the fragmentation after the gamma hydrogen rearrangement to an unsaturated group via a sixmembered intermediate?

9.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

10.
Joseph John Thomson (1856 - 1940), Nobel laureate in physics, is credited with the invention of the mass spectrometer, the discovery of the electron and isotopes of stable elements. A lesser-known fact is his father's profession. What was it?

Czech Museum
of Mass Spectrometry

Our partners

Mass Spectrometry Quiz

Mass Spectrometry Quiz

Thank you for taking our quiz!

1. What ionization technique was used for the first sequencing of peptides by mass spectrometry?

2. Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

3. What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?

4. How many elements of the periodic table have only a single stable isotope?

5. What is the electric charge of an ion with m/z = m?

6. Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?

7. Who built the first mass spectrometer in Czechia?

8. Who first reported the fragmentation after the gamma hydrogen rearrangement to an unsaturated group via a sixmembered intermediate?

9. Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

10. Joseph John Thomson (1856 - 1940), Nobel laureate in physics, is credited with the invention of the mass spectrometer, the discovery of the electron and isotopes of stable elements. A lesser-known fact is his father's profession. What was it?

Czech Museumof Mass Spectrometry

Our partners

1.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?

2.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

3.
What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?

4.
How many elements of the periodic table have only a single stable isotope?

5.
What is the electric charge of an ion with m/z = m?

6.
Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?

7.
Who built the first mass spectrometer in Czechia?

8.
Who first reported the fragmentation after the gamma hydrogen rearrangement to an unsaturated group via a sixmembered intermediate?

9.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

10.
Joseph John Thomson (1856 - 1940), Nobel laureate in physics, is credited with the invention of the mass spectrometer, the discovery of the electron and isotopes of stable elements. A lesser-known fact is his father's profession. What was it?

Czech Museum
of Mass Spectrometry