Mass Spectrometry Quiz

1.
What is the trajectory of a charged particle moving perpendicularly to a uniform magnetic field in a vacuum?
- The particle follows a curved path and continues to follow this path until it forms a complete circle
- The particle follows a helical path
- The particle follows a straight line and accelerates
Your answer:

Correct answer:

The magnetic force is perpendicular to the velocity so that it does no work on the charged particle. The particle’s kinetic energy and speed thus remain constant. The direction of motion is affected but not the speed.
2.
Who made molecular elephants fly?
- John B. Fenn
- Joseph J. Thomson
- W. and O. Wright
Your answer:

Correct answer:

John Fenn was awarded Nobel Prize in Chemistry in 2002 for his work related to electrospray ionization of biological macromolecules. His famous phrase, "we made elephants fly" refers to the ability of electrospray to generate gas-phase ions from big protein molecules.
3.
What is the electric charge of an ion with m/z = m?
- 1 C
- 1.602 176 634 x 10^-19 C
- 1 eV
Your answer:

Correct answer:

The particle carries one elementary charge, the value of which is 1.602 176 634 × 10⁻¹⁹ C (exactly).
4.
The first on-line coupling of gas chromatography to a mass spectrometer was reported in 1959. What type of spectrometer was used for this purpose?
- Double-focusing mass spectrometer
- Time-of-flight mass spectrometer
- Quadrupole mass spectrometer
Your answer:

Correct answer:

The first GC/MS experiments were carried out by Fred McLafferty and Roland Gohlke at Dow Chemical with Bill Wiley and Ian McLaren at Bendix Research Laboratories. They used a Bendix timeof- flight mass spectrometer, which had been commercially introduced in 1956. The instrument was fast enough to keep up with the changing output of the GC column.
5.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?
- Slovakia
- Czechia
- Poland
Your answer:

Correct answer:

The parents of John Zelený, Antonín Zelený and Josefa Pitková, came from Křídla, a small village near Žďár nad Sázavou in Austria-Hungary (now the Czech Republic).
6.
Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?
- Berlin, Germany
- Ostrava, Czechia
- Klosterneuburg, Austria
Your answer:

Correct answer:

Josef Mattauch was born in 1895 in the city of Mährisch Ostrau, in what is now the Czech Republic, then part of the Austrian-Hungarian Empire.
7.
What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?
- The particle follows a curved path and continues to follow this path until it forms a complete circle
- Neither the trajectory nor the velocity of the particle changes
- The particle either accelerates or decelerates, depending on the field direction and the particle charge sign
Your answer:

Correct answer:

If a positive charge is moving in the same direction as the electric field vector the particle's velocity will increase. If it is moving in the opposite direction it will decelerate. If a negative charge is moving in the same direction as the electric field vector the particle will decelerate. If it is moving in the opposite direction it will accelerate.
8.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?
- Burnaby Munson and Frank H. Field
- Michael Barber
- Hans-Dieter Beckey
Your answer:

Correct answer:

Chemical ionization was discovered in the laboratories of the Humble Oil and Refining Company in Baytown, TX. Munson and Field’s seminal paper on chemical ionization was published in 1966. [https://doi.org/10.1021/ja00964a001]
9.
What is the base peak in the mass spectrum?
- The peak with the greatest m/z value
- The peak from which fragments are formed
- The peak that has the greatest intensity
Your answer:

Correct answer:

The base peak is the peak with the greatest intensity among all peaks in the spectrum. The intensity of each peak in the spectrum is expressed as a percentage relative to the intensity of the base peak.
10.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?
- Electron ionization
- Fast atom bombardment
- Matrix-assisted laser desorption/ionization
Your answer:

Correct answer:

Mass spectrometry was used to sequence peptides for the first time in 1959 when K. Biemann described an innovative method based on the reduction of small peptides to polyamino alcohols with characteristic EI spectra. [https://doi.org/10.1021/ja01518a069]

Mass Spectrometry Quiz

Mass Spectrometry Quiz

Thank you for taking our quiz!

1.
What is the trajectory of a charged particle moving perpendicularly to a uniform magnetic field in a vacuum?

2.
Who made molecular elephants fly?

3.
What is the electric charge of an ion with m/z = m?

4.
The first on-line coupling of gas chromatography to a mass spectrometer was reported in 1959. What type of spectrometer was used for this purpose?

5.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

6.
Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?

7.
What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?

8.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

9.
What is the base peak in the mass spectrum?

10.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?

Czech Museum
of Mass Spectrometry

Our partners

Mass Spectrometry Quiz

Mass Spectrometry Quiz

Thank you for taking our quiz!

1. What is the trajectory of a charged particle moving perpendicularly to a uniform magnetic field in a vacuum?

2. Who made molecular elephants fly?

3. What is the electric charge of an ion with m/z = m?

4. The first on-line coupling of gas chromatography to a mass spectrometer was reported in 1959. What type of spectrometer was used for this purpose?

5. John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

6. Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?

7. What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?

8. Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

9. What is the base peak in the mass spectrum?

10. What ionization technique was used for the first sequencing of peptides by mass spectrometry?

Czech Museumof Mass Spectrometry

Our partners

1.
What is the trajectory of a charged particle moving perpendicularly to a uniform magnetic field in a vacuum?

2.
Who made molecular elephants fly?

3.
What is the electric charge of an ion with m/z = m?

4.
The first on-line coupling of gas chromatography to a mass spectrometer was reported in 1959. What type of spectrometer was used for this purpose?

5.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

6.
Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?

7.
What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?

8.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

9.
What is the base peak in the mass spectrum?

10.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?

Czech Museum
of Mass Spectrometry